Breast Carcinoma
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study of germline variants and breast cancer-specific mortality.
|
30787463 |
2019 |
Diastolic blood pressure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.
|
30578418 |
2019 |
Systolic Pressure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.
|
30578418 |
2019 |
Chronic Periodontitis
|
0.030 |
Biomarker
|
disease |
BEFREE |
In summary, our findings provide direct evidence for the association of NIN and SIGLEC5 with CP susceptibility.
|
30765789 |
2019 |
Choroid Plexus Papilloma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Five transcription factors (TFs) belonging to three distinct TF families: one TCP (OsPCF2), one CPP (OsCPP5) and three NIN-like (OsNIN-like2, OsNIN-like3 and OsNIN-like4) were identified as binding to OsNHX1 promoter.
|
27766460 |
2017 |
TROPICAL CALCIFIC PANCREATITIS
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Five transcription factors (TFs) belonging to three distinct TF families: one TCP (OsPCF2), one CPP (OsCPP5) and three NIN-like (OsNIN-like2, OsNIN-like3 and OsNIN-like4) were identified as binding to OsNHX1 promoter.
|
27766460 |
2017 |
Platelet mean volume determination (procedure)
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
SECKEL SYNDROME 7
|
0.700 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Identification of a Ninein (NIN) mutation in a family with spondyloepimetaphyseal dysplasia with joint laxity (leptodactylic type)-like phenotype.
|
23665482 |
2014 |
Lupus Erythematosus, Systemic
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
|
24925725 |
2014 |
Lupus Nephritis
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
|
24925725 |
2014 |
Chronic Periodontitis
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
Six genes showed evidence of statistically significant association: 4 with severe CP (NIN, p = 1.6 × 10(-7); ABHD12B, p = 3.6 × 10(-7); WHAMM, p = 1.7 × 10(-6); AP3B2, p = 2.2 × 10(-6)) and 2 with high periodontal pathogen colonization (red complex-KCNK1, p = 3.4 × 10(-7); Porphyromonas gingivalis-DAB2IP, p = 1.0 × 10(-6)).
|
25056994 |
2014 |
Seckel syndrome
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Moreover, compound heterozygous missense mutations at more N-terminal positions of Ninein have very recently been identified in a family with microcephalic primordial dwarfism.
|
23665482 |
2014 |
Spondyloepimetaphyseal dysplasia with multiple dislocations
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
We present several lines of evidence that mutant Ninein is most likely causative for the SEMDJL2-like phenotype.
|
23665482 |
2014 |
Chronic Periodontitis
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
We detected no genome-wide significant association signals for CP; however, we found suggestive evidence of association (P < 5 × 10(-6)) for six loci, including NIN, NPY, WNT5A for severe CP and NCR2, EMR1, 10p15 for moderate CP.
|
23459936 |
2013 |
Carcinoma
|
0.010 |
Biomarker
|
group |
BEFREE |
NIN/RPN Binding protein 1 homologue (NOBp1), encoded by NOB1 gene, was reported to play an essential role in the oncogenesis and prognosis of carcinomas.
|
24133592 |
2013 |
SECKEL SYNDROME 7
|
0.700 |
GermlineCausalMutation
|
disease |
ORPHANET |
Novel microcephalic primordial dwarfism disorder associated with variants in the centrosomal protein ninein.
|
22933543 |
2012 |
SECKEL SYNDROME 7
|
0.700 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Novel microcephalic primordial dwarfism disorder associated with variants in the centrosomal protein ninein.
|
22933543 |
2012 |
SECKEL SYNDROME 7
|
0.700 |
GeneticVariation
|
disease |
UNIPROT |
Novel microcephalic primordial dwarfism disorder associated with variants in the centrosomal protein ninein.
|
22933543 |
2012 |
Seckel syndrome
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Novel microcephalic primordial dwarfism disorder associated with variants in the centrosomal protein ninein.
|
22933543 |
2012 |
Chronic myeloproliferative disorder
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
We identified a novel clinical subtype of MPD in two sisters who have rare variants in NIN.
|
22933543 |
2012 |
Breast Carcinoma
|
0.110 |
GeneticVariation
|
disease |
BEFREE |
A two SNP combination of rs10145182 in NIN and rs2134808 in the TUBG1 locus (P-interaction = 0.00001), suggested SNPs in mediators of microtubule nucleation from the centrosome contribute to breast cancer.
|
20508983 |
2011 |
Malignant neoplasm of breast
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
A two SNP combination of rs10145182 in NIN and rs2134808 in the TUBG1 locus (P-interaction = 0.00001), suggested SNPs in mediators of microtubule nucleation from the centrosome contribute to breast cancer.
|
20508983 |
2011 |
Neoplasm Metastasis
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Our data clearly reflect such tumor promotion, showing that deregulation of key proteins involved in apoptosis (BCL2-related protein A1 and Fas apoptotic inhibitory molecule), cell cycle checkpoints (AKIP, SCYL1, and NIN), and metastasis (matrix metalloproteinase 1) is closely correlated with the levels of EBV gene expression in NPC.
|
16912175 |
2006 |
Nodule
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Nodule-in-nodule-type hepatocellular carcinoma (NIN-HCC) is a useful model to illustrate the multi-step nature of hepatocarcinogenesis.
|
16462536 |
2006 |
Hepatocarcinogenesis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Nodule-in-nodule-type hepatocellular carcinoma (NIN-HCC) is a useful model to illustrate the multi-step nature of hepatocarcinogenesis.
|
16462536 |
2006 |